Senior Scientist at AstraZeneca in Gothenburg

Senior Scientist, Biomarker Discovery and Development at AstraZeneca in Gothenburg!

Do you have expertise in Biomarker Discovery and Development in Cardiovascular, Metabolic and Renal Diseases? Would you like to apply your expertise at a company that are following the science and turn ideas into life changing medicines? If this matches your ambition and skills, then you might be the one AstraZeneca in Gothenburg is looking for! Apply today!

Purpose, Offer and Benefits

As a Biomarker Scientist, you will be a key member in the Biomarker Discovery and Development team and play a key role from preclinical to clinical biomarker delivery for progressing projects and science. In this role, you will have the opportunity to try novel techniques and ideas for identification of new biomarkers.

Your Responsibilities

This role will be primarily lab based and contribute to building the biomarker strategy.

You will be responsible for:

• Driving biomarker discovery for identification of target-related biomarkers and for precision medicine hypothesis generation
• Delivering high quality and robust biomarker data package to support project progression across the CVRM project portfolio
• Implementation of novel biomarker methods e.g. mass spectrometry-based approaches using state of the art analytical techniques, biomarker analysis, reporting biomarker data and evaluation to the project teams
• Collaboration for successful delivery of drug projects and you will work closely with scientists/teams from a wide range of different functions within AstraZeneca. 

The Bigger Picture

As a Senior Scientist, Biomarker Discovery and Development you will join the Biomarker team in the department of Translational Science and Experimental Medicine (TS&EM) within Early Cardiovascular Renal and Metabolic Diseases (CVRM) therapeutic area at AstraZeneca in Gothenburg, Sweden.

Early Cardiovascular, Renal and Metabolism (CVRM) is accountable for the discovery and development (up to phase II) of new medicines within three main strategic areas - cardiovascular/heart failure, metabolism (diabetes and NASH) and chronic kidney disease. The Translational Sciences and Experimental Medicine (TS&EM) Department within Early CVRM has the remit to bridge early and late drug development by providing: i) target validation in humans; ii) biomarker strategy (target engagement & proof of mechanism biomarkers); iii) precision medicine strategies; and iv) human data-driven novel target identification

The selection process is ongoing and the position can be filled before the last apply-date. This position is a consultant assignment and is a full-time job and will last for 1 year. This means that you will be employed by TNG  during this time.

Our Expectations

Essential for the role

• PhD or equivalent education in analytical chemistry or related scientific discipline
• A solid background in the field of analytical chemistry with focus on various immunoassays platforms as well as liquid chromatography and mass spectrometry.
• Expertise in analyzing endogenous biomarkers using immunoassay platforms (ELISA, MSD, Luminex, SIMOA, Clinical analyzers)
• Expertise in quantitatively analyzing endogenous biomarkers such as polar metabolites, lipids, peptides and proteins using liquid chromatography mass spectrometry
• Hands on research experience of ex vivo work on urinary extracellular vesicles and various blood cell populations
• Ability to plan and report all work to appropriate standards (Good Laboratory Standard, GLS)
• Good project management and matrix leadership skills, ability to collaborate well cross functions

We want the right candidate to have a passion for delivering and promoting excellence in science and an excellent English communication skills, both verbal and written.